BDBM50221137 4-((S)-1-(2-(4-((R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl)piperazin-1-yl)-5-(trifluoromethyl)phenyl)-3-methylbutylamino)butanoic acid::CHEMBL262320

SMILES CC(C)C[C@H](NCCCC(O)=O)c1cc(ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O)C(F)(F)F

InChI Key InChIKey=XNPVNWIDDNEPTG-LMSSTIIKSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221137   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50221137(4-((S)-1-(2-(4-((R)-3-(2,4-dichlorophenyl)-2-(2-ox...)
Affinity DataKi:  40nMAssay Description:Binding affinity at human MC4RMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50221137(4-((S)-1-(2-(4-((R)-3-(2,4-dichlorophenyl)-2-(2-ox...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of microsomal CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50221137(4-((S)-1-(2-(4-((R)-3-(2,4-dichlorophenyl)-2-(2-ox...)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at human MC4R expressed in HEK293 cells by cAMP accumulation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed