BDBM50228550 (R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrrolidin-1-yl)propoxy)phenyl)piperazin-2-one formic acid::CHEMBL239299

SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)N1CCN(CC1=O)C(=O)c1ccc(F)cc1F

InChI Key InChIKey=LAQGPQNMQRFDIM-GOSISDBHSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50228550   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of human CYP3A4 using 7-benzloxyquinolone substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50228550((R)-4-(2,4-difluorobenzoyl)-1-(4-(3-(2-methylpyrro...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP3A4 using 7-{3-(4-phenylpiperazin-1-ylmethyl)benzyl}resorufin substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed