BDBM50232116 1-(1H-indazol-4-yl)-3-(7-(trifluoromethyl)-3,4-dihydro-2H-chromen-4-yl)urea::CHEMBL254225

SMILES FC(F)(F)c1ccc2C(CCOc2c1)NC(=O)Nc1cccc2[nH]ncc12

InChI Key InChIKey=LNRLQTQYVBBJBO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50232116   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50232116(1-(1H-indazol-4-yl)-3-(7-(trifluoromethyl)-3,4-dih...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at human TRPV1 assessed as inhibition of calcium influxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50232116(1-(1H-indazol-4-yl)-3-(7-(trifluoromethyl)-3,4-dih...)
Affinity DataIC50:  11nMAssay Description:Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed