BDBM50236948 CHEMBL4080095

SMILES O=C(\C=C\c1cccnc1)c1ccc2ccc3ccccc3c2c1

InChI Key InChIKey=GONLWTWOUQDZRN-KPKJPENVSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50236948   

TargetCytochrome P450 3A4(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human liver CYP3A4 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of human liver CYP2D6 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using EOMCC as substrate after 10 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human liver CYP2C19 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50:  122nMAssay Description:Inhibition of human liver CYP1A1 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using 7-ethoxyresorufin as substrate after 10 mins by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of human liver CYP2C9 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using DBF as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50:  48nMAssay Description:Inhibitory concentration against progesterone stimulated alkaline phosphatase activity in T47D human breast carcinoma cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50236948(CHEMBL4080095)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human liver CYP1A2 expressed in Saccharomyces cerevisiae YY7 microsomal membranes using CEC as substrate after 10 mins by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed