BDBM50238020 CHEMBL4082172

SMILES NC(CO)(CO)CO.OC(=O)CCc1noc2ccc(Cl)cc12

InChI Key InChIKey=OAYCUGWKROPKGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50238020   

TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238020(CHEMBL4082172)
Affinity DataIC50:  25nMAssay Description:Inhibition of recombinant full-length human N-terminal GST tagged KMO expressed in baculovirus infected Sf9 insect cell membranes using L-kynurenine ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKynurenine 3-monooxygenase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50238020(CHEMBL4082172)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of full length human KMO expressed in HEK293 cells using L-kynurenine as substrate measured after 20 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed