BDBM50239754 2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imidazol-5-yl)piperazin-1-yl)ethanol::CHEMBL259185

SMILES CC(C)(C)Sc1nc2cc(Cl)c(cc2[nH]1)N1CCN(CCO)CC1

InChI Key InChIKey=NXTWTUDFHBDVOS-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50239754   

TargetDelta-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]naltrindole from human delta opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]Tyr14-NC/OFQ from human ORL1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  17nMAssay Description:Displacement of [125I]Tyr14-NC from human ORL1 receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  4.40E+3nMAssay Description:Displacement of [3H]diprenorphin from human mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]U-69593 from human cloned kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human ORL1 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human ORL1 receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  4.40E+3nMAssay Description:Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50239754(2-(4-(2-(tert-butylthio)-6-chloro-3H-benzo[d]imida...)
Affinity DataIC50:  120nMAssay Description:Displacement of [3H]U-69593 from human kappa opioid receptor expressed in CHO cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed