BDBM50243937 (1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0]hexane::CHEMBL451527

SMILES Clc1ccc(cc1Cl)[C@]12C[C@@H]1CNC2

InChI Key InChIKey=BSMNRYCSBFHEMQ-LDYMZIIASA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50243937   

TargetTransporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  51nMAssay Description:Inhibition of norepinephrine uptake at NET in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of serotonin uptake at SERT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  96nMAssay Description:Inhibition of dopamine uptake at human cloned DATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  23nMAssay Description:Inhibition of norepinephrine uptake at human cloned NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  12nMAssay Description:Inhibition of serotonin uptake at human cloned SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50243937((1R,5S)-1-(3,4-dichlorophenyl)-3-aza-bicyclo[3.1.0...)
Affinity DataIC50:  260nMAssay Description:Inhibition of dopamine uptake at cloned DAT in rat brain synaptosomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed