BDBM50244036 Beta-CCT::CHEMBL509197::tert-butyl 9H-pyrido[3,4-b]indole-3-carboxylate
SMILES CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccccc21
InChI Key InChIKey=FVFFDKKTXYVCCW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50244036
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human recombinant GABAA alpha1 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 0.720nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Binding affinity to human recombinant GABAA alpha2 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 18.9nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 19nMAssay Description:Binding affinity to human recombinant GABAA alpha3 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Binding affinity to human recombinant GABAA alpha5 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 111nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4(Rattus norvegicus (Rat))
National Institute of Diabetes, Digestive and Kidney Diseases
Curated by PDSP Ki Database
National Institute of Diabetes, Digestive and Kidney Diseases
Curated by PDSP Ki Database
Affinity DataKi: 1.00E+3nMAssay Description:Binding affinity to human recombinant GABAA alpha4 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-6(RAT)
National Institute of Diabetes, Digestive and Kidney Diseases
Curated by PDSP Ki Database
National Institute of Diabetes, Digestive and Kidney Diseases
Curated by PDSP Ki Database
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee
Curated by ChEMBL
University Of Wisconsin-Milwaukee
Curated by ChEMBL
Affinity DataKi: >5.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to human recombinant GABAA alpha6 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 111nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair