BDBM50244812 CHEMBL4097113
SMILES CCCNNC(=O)CCCCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)c1ccc(OC)cc1
InChI Key InChIKey=ZCZXFHBXRHZTID-MHZLTWQESA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50244812
TargetHistone deacetylase 2(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataIC50: 199nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC2 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataIC50: 53nMAssay Description:Inhibition of full length recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus expression system using Boc-Lys(acetyl)-AMC as ...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of HDAC6 (unknown origin) using Boc-Lys(acetyl)-AMC as substrate preincubated for 1 hr followed by substrate addition measured after 2 hrs...More data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Homo sapiens (Human))
Medical University of South Carolina
Curated by ChEMBL
Medical University of South Carolina
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged HDAC3/N-terminal GST-tagged NCOR2 co-expressed in baculovirus expression system usi...More data for this Ligand-Target Pair