BDBM50248211 CHEMBL526305::N-cyclopropyl-N-((1s,4R)-4-cyclopropyl-4-hydroxycyclohexyl)-4-((S)-1,1,1-trifluoro-2-hydroxypropan-2-yl)benzamide::N-cyclopropyl-N-(cis-4-cyclopropyl-4-hydroxycyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide
SMILES C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)[C@H]1CC[C@@](O)(CC1)C1CC1)C(F)(F)F
InChI Key InChIKey=SWXZIRVTPISJMP-SESVDKBCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50248211
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant full length 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of conversion of [3H]cortisone to [3H]cortis...More data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of human recombinant full length 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of conversion of [3H]cortisone to [3H]cortis...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant full length 11beta-HSD1 expressed in human adipocytes assessed as inhibition of conversion of [3H]cortisone to [3H]co...More data for this Ligand-Target Pair
Affinity DataIC50: 244nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of FLAG-tagged full length human 11beta-HSD1 expressed in baculovirus-infected Trichoplusia ni Hi5 cells assessed as reduction of [3H]cort...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in absence of NADPHMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of full length human recombinant 11beta-HSD1 expressed in HEK293 cells in presence of 3% human serum albuminMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of human full length 11beta-HSD1 assessed as inhibition of conversion of [3H]cortisone to [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair