BDBM50255029 CHEMBL480219::{1-[4-((3R,5S)-3,5-Dimethyl-piperazin-1-ylmethyl)-phenyl]-1H-imidazol-2-yl}-[4-(3-fluoro-phenylamino)-piperidin-1-yl]-methanone
SMILES C[C@H]1CN(Cc2ccc(cc2)-n2ccnc2C(=O)N2CCC(CC2)Nc2cccc(F)c2)C[C@@H](C)N1
InChI Key InChIKey=BKNPWPRZETXJRA-OYRHEFFESA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50255029
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using diethoxyfluorescein substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using phenylpiperazinylmethylbenzylresofurin substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 15.8nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: >2.51E+4nMAssay Description:Inhibition of human ERG bindingMore data for this Ligand-Target Pair
TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 501nMAssay Description:Inhibition of human Ghrelin receptorMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair