BDBM50260999 CHEMBL4099210

SMILES CCN([C@@H](C)Cc1noc(n1)-c1ccc(F)cn1)C(=O)c1cc(F)ccc1-n1nccn1

InChI Key InChIKey=HCPNIIGCYVOXFN-ZDUSSCGKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50260999   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260999(CHEMBL4099210)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human OX1R expressed in CHO cells assessed as reduction in [Ala6,12]orexin-A-induced intracellular Ca2+ mobilization incubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOrexin receptor type 2(Homo sapiens (Human))
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50260999(CHEMBL4099210)
Affinity DataIC50:  887nMAssay Description:Inhibition of trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed