BDBM50263450 CHEMBL4083713

SMILES CN1C(=O)N2CC(c3c(C2)n(Cc2ccc(cc2)C(=O)NO)c2ccccc32)C1=S

InChI Key InChIKey=SKQXWXDNMCCCFP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50263450   

TargetHistone deacetylase 6(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263450(CHEMBL4083713)
Affinity DataKi:  0.880nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged HDAC6 expressed in baculovirus-infected Sf9 insect cells using RHKK(Ac)AMC as subst...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263450(CHEMBL4083713)
Affinity DataKi:  701nMAssay Description:Inhibition of recombinant human C-terminal His-tagged HDAC8 (1 to 377 residues) expressed in baculovirus-infected insect cells using RHK(Ac)K(Ac)AMC ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL
LigandPNGBDBM50263450(CHEMBL4083713)
Affinity DataKi:  943nMAssay Description:Inhibition of full length recombinant human C-terminal GST-tagged HDAC2 expressed in baculovirus-infected insect cells using RHKK(Ac)AMC as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed