BDBM50266232 CHEMBL458009::Diethyl-[3-(4-naphtho[1,2-d]oxazol-2-yl-phenoxy)-propyl]-amine

SMILES CCN(CC)CCCOc1ccc(cc1)-c1nc2c(ccc3ccccc23)o1

InChI Key InChIKey=DLJQPWBVDBULKI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266232   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  4.05E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50266232(CHEMBL458009 | Diethyl-[3-(4-naphtho[1,2-d]oxazol-...)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of of PTP1B (unknown origin) assessed as residual enzyme activity in presence of Triton X-100More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed