BDBM50276966 4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-N-(3-(trifluoromethyl)phenyl)isothiazole-3-carboxamide::CHEMBL462527

SMILES FC(F)(F)c1cccc(NC(=O)c2nscc2NCCc2ccc3OCOc3c2)c1

InChI Key InChIKey=AXLWRBCJXLSOFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50276966   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50276966(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-N-(3-(t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR1 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50276966(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-N-(3-(t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) assessed as blockade of pGAT-biotin phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Decode

Curated by ChEMBL
LigandPNGBDBM50276966(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-N-(3-(t...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin) expressed in HEK293 cells assessed as inhibition of receptor phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed