BDBM50293141 CHEMBL503212::N-cyclopropyl-4-(6-(thiophen-2-yl)pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

SMILES C1CC1Nc1nccc(n1)-c1cnn2nc(ccc12)-c1cccs1

InChI Key InChIKey=ULKTXVYWINYRCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293141   

TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293141(CHEMBL503212 | N-cyclopropyl-4-(6-(thiophen-2-yl)p...)
Affinity DataIC50: >3.20E+4nMAssay Description:Inhibition of GSK3beta by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293141(CHEMBL503212 | N-cyclopropyl-4-(6-(thiophen-2-yl)p...)
Affinity DataIC50:  250nMAssay Description:Inhibition of CDK4 by radioactive glutathione plate-binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed