BDBM50293513 2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine::CHEMBL564660

SMILES N(c1ccncc1)c1nc(nc2ccccc12)-c1ccccc1

InChI Key InChIKey=QGWNGFYEPGNYNY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293513   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  194nMAssay Description:Inhibition of human ALK5 kinase expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  2.47E+3nMAssay Description:Inhibition of TGFbeta-induced ALK5 in human HepG2 cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293513(2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine | CHEM...)
Affinity DataIC50:  1.27E+3nMAssay Description:Inhibition of GST-fused p38alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed