BDBM50293579 3-(4-Phenylthiazol-2-ylamino)phenol::CHEMBL554135

SMILES Oc1cccc(Nc2nc(cs2)-c2ccccc2)c1

InChI Key InChIKey=AGQNMYLPVLOPBV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293579   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50293579(3-(4-Phenylthiazol-2-ylamino)phenol | CHEMBL554135)
Affinity DataIC50:  3.70E+3nMAssay Description:Inhibition of partially purified recombinant 5-lipoxygenase (unknown origin) using arachidonic acid as substrate preincubated for 15 mins before subs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Sus scrofa (Pig))
Boston College

Curated by ChEMBL
LigandPNGBDBM50293579(3-(4-Phenylthiazol-2-ylamino)phenol | CHEMBL554135)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of pig FBPase expressed in Escherichia coli EK1601 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50293579(3-(4-Phenylthiazol-2-ylamino)phenol | CHEMBL554135)
Affinity DataIC50:  8.30E+3nMAssay Description:Inhibition of 5-lipoxygenase in human PMNL using arachidonic acid as substrate preincubated for 15 mins before substrate addition measured after 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed