BDBM50293854 2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluoromethoxy)-1H-indol-3-yl)methyl)phenoxy)acetic acid::CHEMBL556073

SMILES Cc1c(Cc2cccc(OCC(O)=O)c2)c2cc(OC(F)(F)F)ccc2n1C(=O)c1ccc(Cl)cc1

InChI Key InChIKey=MAPNDWGAIMFUJK-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293854   

TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293854(2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluorome...)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of human PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293854(2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluorome...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293854(2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluorome...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at human PPARalpha receptor expressed in african green monkey COS1 cells cotransfected with fused yeast Gal4-DBD by transactivation ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Mus musculus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293854(2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluorome...)
Affinity DataEC50: >3.00E+3nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293854(2-(3-((1-(4-chlorobenzoyl)-2-methyl-5-(trifluorome...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed