BDBM50295924 4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-biphenyl-2-ol::CHEMBL557713

SMILES COc1ccc(cc1\C=C/C)-c1cc(CC=C)ccc1O

InChI Key InChIKey=IDZDKMNEPBYXQX-ALCCZGGFSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295924   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of 5LOX-mediated LTB4 formation in stimulated human polymorphonuclear leukocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2(Homo sapiens (Human))
University Of Vienna

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataEC50:  1.97E+4nMAssay Description:Modulation of GABA Aalpha1beta2 receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current at holding pot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  900nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Karl-Franzens-Universit£T Graz

Curated by ChEMBL
LigandPNGBDBM50295924(4'-Methoxy-3'-(Z)-propenyl)-5-(2-propenyl)-bipheny...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of COX1 in ram seminal vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed