BDBM50301015 4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1-oxo-1lambda*4*-thiomorpholin-4-ylmethyl)-pyridin-2-yl]-quinoline-3-carbonitrile::CHEMBL566577

SMILES COc1cc(Nc2c(cnc3cc(ccc23)-c2ccc(CN3CCS(=O)CC3)cn2)C#N)c(Cl)cc1Cl

InChI Key InChIKey=BNIHZQHNNOVQNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50301015   

TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301015(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1-oxo...)
Affinity DataIC50:  96nMAssay Description:Inhibition of human Src expressed in rat fibroblasts assessed as anchorage independent growth after 3 daysMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50301015(4-(2,4-Dichloro-5-methoxy-phenylamino)-7-[5-(1-oxo...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed