BDBM50304085 CHEMBL607819::N-(2-(3,4-Dichlorophenylamino)ethyl)-2-(4-(methylsulfonamido)phenoxy)acetamide

SMILES CS(=O)(=O)Nc1ccc(OCC(=O)NCCNc2ccc(Cl)c(Cl)c2)cc1

InChI Key InChIKey=RASKYMQICXHQMH-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50304085   

TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(CHEMBL607819 | N-(2-(3,4-Dichlorophenylamino)ethyl...)
Affinity DataKi:  119nMAssay Description:Displacement of [3H]ifenprodil form NR2B receptor in Wistar rat cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(CHEMBL607819 | N-(2-(3,4-Dichlorophenylamino)ethyl...)
Affinity DataIC50:  8.20E+4nMAssay Description:Antagonist activity at rat recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(CHEMBL607819 | N-(2-(3,4-Dichlorophenylamino)ethyl...)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at rat recombinant NR1/NR2B receptor expressed in frog oocytes assessed as inhibition of glutamate/glycine-induced current by two...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(CHEMBL607819 | N-(2-(3,4-Dichlorophenylamino)ethyl...)
Affinity DataIC50:  57nMAssay Description:Antagonist activity at wild type rat NR1/NR2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curren...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2C(RAT)
Emory University

Curated by ChEMBL
LigandPNGBDBM50304085(CHEMBL607819 | N-(2-(3,4-Dichlorophenylamino)ethyl...)
Affinity DataIC50:  5.80E+4nMAssay Description:Antagonist activity at rat recombinant NR1/NR2C receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced curr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed