BDBM50304286 2-Amino-1-(4-methoxyphenyl)-6,7-methylenedioxy-2H-isoquinolin-3-one::CHEMBL596442

SMILES COc1ccc(cc1)-c1n(N)c(=O)cc2cc3OCOc3cc12

InChI Key InChIKey=BNKGRGSYPOHWKB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50304286   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Universit£

Curated by ChEMBL
LigandPNGBDBM50304286(2-Amino-1-(4-methoxyphenyl)-6,7-methylenedioxy-2H-...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50304286(2-Amino-1-(4-methoxyphenyl)-6,7-methylenedioxy-2H-...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human cathepsin LMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50304286(2-Amino-1-(4-methoxyphenyl)-6,7-methylenedioxy-2H-...)
Affinity DataKi:  1.63E+4nMAssay Description:Inhibition of human cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed