BDBM50311029 CHEMBL1077841::N-(cyanomethyl)-4-(2-(4-thiomorpholinophenylamino)pyrimidin-4-yl)benzamide

SMILES O=C(NCC#N)c1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCSCC2)n1

InChI Key InChIKey=PULGHSXSJBTNHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311029   

TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311029(CHEMBL1077841 | N-(cyanomethyl)-4-(2-(4-thiomorpho...)
Affinity DataIC50:  364nMAssay Description:Inhibition of GST-tagged JAK3 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Cytopia Research

Curated by ChEMBL
LigandPNGBDBM50311029(CHEMBL1077841 | N-(cyanomethyl)-4-(2-(4-thiomorpho...)
Affinity DataIC50:  69nMAssay Description:Inhibition of GST-tagged JAK2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed