BDBM50315062 1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-(3,6-dihydro-2H-pyran-4-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-methylpiperazin-1-yl)phenyl)urea::CHEMBL1091349

SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)C2=CCOCC2)N2C3CCC2COC3)cc1

InChI Key InChIKey=NDLMLALBYLJOIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50315062   

LigandPNGBDBM50315062(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-(3...)
Affinity DataIC50:  51nMAssay Description:Inhibition of PI3Kalpha after 15 to 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50315062(1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-(3...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed