BDBM50316278 2-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-1H-pyrazolo-[3,4-d]pyrimidin-6-yl]phenyl}-N-methylacetamide::CHEMBL1095623

SMILES CNC(=O)Cc1ccc(cc1)-c1nc(N2CCOCC2)c2cnn(C3CCN(Cc4ccccc4)CC3)c2n1

InChI Key InChIKey=WLZGENRVUAPESL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50316278   

LigandPNGBDBM50316278(2-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibition of PI3Kalpha by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50316278(2-{4-[1-(1-Benzylpiperidin-4-yl)-4-morpholin-4-yl-...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human mTOR (1360-2549 amino acids) expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed