BDBM50316790 2-{5-(4-Hydroxyphenethoxy)-1-[5-(4-methoxyphenyl)-pentyl]-1H-indole-3-yl}ethanamine hydrochloride::CHEMBL1098121

SMILES COc1ccc(CCCCCn2cc(CCN)c3cc(OCCc4ccc(O)cc4)ccc23)cc1

InChI Key InChIKey=POLXUFYBMIRDEG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50316790   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316790(2-{5-(4-Hydroxyphenethoxy)-1-[5-(4-methoxyphenyl)-...)
Affinity DataIC50:  2.05E+3nMAssay Description:Inhibition of VEGFR3 after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316790(2-{5-(4-Hydroxyphenethoxy)-1-[5-(4-methoxyphenyl)-...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of EGFR after 30 mins by chemiluminescence ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316790(2-{5-(4-Hydroxyphenethoxy)-1-[5-(4-methoxyphenyl)-...)
Affinity DataIC50:  2.17E+3nMAssay Description:Noncompetitive inhibition of VEGFR2 after 30 mins by chemiluminescence ELISA in presence of 25 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Universit£T Leipzig

Curated by ChEMBL
LigandPNGBDBM50316790(2-{5-(4-Hydroxyphenethoxy)-1-[5-(4-methoxyphenyl)-...)
Affinity DataIC50:  3.21E+3nMAssay Description:Noncompetitive inhibition of IGF1R after 30 mins by chemiluminescence ELISA in presence of 50 uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed