BDBM50318414 7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahydro-6beta,14beta-endoethenooripavine::CHEMBL1094466

SMILES CO[C@]12C=C[C@@]3(C[C@@H]1C(C)(C)C)[C@H]1Cc4ccc(O)c5O[C@@H]2[C@]3(CCN1C)c45

InChI Key InChIKey=IXPHHHSWTVEWTP-VWUQPSBSSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50318414   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataIC50:  0.540nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataIC50:  1.35E+3nMAssay Description:Displacement of [3H]deltorphin-2 from delta opioid receptor from Wistar rat brain by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(MOUSE)
University Of Debrecen

Curated by ChEMBL
LigandPNGBDBM50318414(7alpha-(1-Hydroxy-1-methyl-ethyl)-6,7,8,14-tetrahy...)
Affinity DataEC50:  11.9nMAssay Description:Agonist activity at mu opioid receptor in Swiss albino mouse ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed