BDBM50319978 CHEMBL1084210::N-(naphthalen-1-ylmethyl)-2-(pyrrolidin-1-yl)pyrimidin-4-amine

SMILES C(Nc1ccnc(n1)N1CCCC1)c1cccc2ccccc12

InChI Key InChIKey=NAYIVRUMIMUOGQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50319978   

TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319978(CHEMBL1084210 | N-(naphthalen-1-ylmethyl)-2-(pyrro...)
Affinity DataIC50:  5.80E+3nMAssay Description:Inhibition of electric eel AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319978(CHEMBL1084210 | N-(naphthalen-1-ylmethyl)-2-(pyrro...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of human AChE incubated with compounf for 5 mins before addition of substrate acetylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxylic ester hydrolase(Equus caballus (Horse))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319978(CHEMBL1084210 | N-(naphthalen-1-ylmethyl)-2-(pyrro...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of equine BChE incubated with compounf for 5 mins before addition of substrate S-butyrylthiocholine iodide by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Equus caballus (Horse))
University Of Waterloo

Curated by ChEMBL
LigandPNGBDBM50319978(CHEMBL1084210 | N-(naphthalen-1-ylmethyl)-2-(pyrro...)
Affinity DataIC50:  8.90E+3nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed