BDBM50320794 CHEMBL1165306::Methyl4-[(5-[(2,4-diamino-6-quinazolinyl)methyl]amino-2-methoxyphenoxy)methyl]benzene carboxylate
SMILES COC(=O)c1ccc(COc2cc(NCc3ccc4nc(N)nc(N)c4c3)ccc2OC)cc1
InChI Key InChIKey=BYCSTMIHRAHFHA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50320794
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataKi: 24.5nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University Of Alabama
Curated by ChEMBL
University Of Alabama
Curated by ChEMBL
Affinity DataIC50: 57.5nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of human DHFR by spectrophotometric assayMore data for this Ligand-Target Pair