BDBM50323360 4-(7-benzyl-6-oxo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-5-yl)benzonitrile::CHEMBL1209775

SMILES O=C1C(c2ccc(cc2)C#N)n2cncc2CN1Cc1ccccc1

InChI Key InChIKey=PKHXGYUUXXTTBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50323360   

TargetCytochrome P450 11B1, mitochondrial(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323360(4-(7-benzyl-6-oxo-5,6,7,8-tetrahydroimidazo[1,5-a]...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant CYP11B1 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 11B2, mitochondrial(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50323360(4-(7-benzyl-6-oxo-5,6,7,8-tetrahydroimidazo[1,5-a]...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant CYP11B2 by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed