BDBM50324245 (R)-(-)-3-(5-Cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-1-yl)-N,N-dimethylpropan-1-amine::CHEMBL1214844

SMILES CN(C)CCC[C@@]1(OCc2cc(\C=C\c3ccc(cc3)C#N)ccc12)c1ccc(F)cc1

InChI Key InChIKey=NDBCFJNXVCOSEG-BBELGVGPSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50324245   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50324245((R)-(-)-3-(5-Cyano-1-(4-fluorophenyl)-1,3-dihydroi...)
Affinity DataKi:  28.3nMAssay Description:Displacement of [3H]citalopram from SERT in rat brain stem by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50324245((R)-(-)-3-(5-Cyano-1-(4-fluorophenyl)-1,3-dihydroi...)
Affinity DataKi:  4.98E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat frontal cortex by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50324245((R)-(-)-3-(5-Cyano-1-(4-fluorophenyl)-1,3-dihydroi...)
Affinity DataKi:  7.98E+3nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rat caudate-putamen by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed