BDBM50330030 CHEMBL1269632::[(3-Bromophenyl)-(3-hydroxyphenyl)-ketone]thiosemicarbazone

SMILES NC(=S)NN=C(c1cccc(O)c1)c1cccc(Br)c1

InChI Key InChIKey=ZDBKSZKTCPOBFR-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50330030   

TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330030(CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...)
Affinity DataKi:  3.70nMAssay Description:Covalent/reversible inhibition of human liver cathepsin-L using Z-FR-AMC as substrate preincubated for 5 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330030(CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human liver cathepsin L after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Baylor University

Curated by ChEMBL
LigandPNGBDBM50330030(CHEMBL1269632 | [(3-Bromophenyl)-(3-hydroxyphenyl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human liver cathepsin B after 5 mins by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed