BDBM50330999 CHEMBL1277708::[5-(4-Hydroxy-3-methylphenyl)-2-thienyl](3-hydroxyphenyl)-methanone

SMILES Cc1cc(ccc1O)-c1ccc(s1)C(=O)c1cccc(O)c1

InChI Key InChIKey=SHMWBFSCYSEXIS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50330999   

Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  27nMAssay Description:Inhibition of 17beta-HSD1 in human T47D cells using [2,4,6,7-3H]-estrone as substrate after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human placenta 17beta-HSD1 using [2,4,6,7-3H]-estrone as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  382nMAssay Description:Inhibition of human microsomal 17beta-HSD2 in cell-free system using [2,4,6,7-3H]E2 as substrate after 20 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  382nMAssay Description:Inhibition of human placenta 17beta-HSD2 using [2,4,6,7-3H]-17beta-estradiol as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

Curated by ChEMBL
LigandPNGBDBM50330999(CHEMBL1277708 | [5-(4-Hydroxy-3-methylphenyl)-2-th...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human cytosolic 17beta-HSD1 in cell-free system using [2,4,6,7-3H]E1 as substrate after 10 mins by radioflow detectorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed