BDBM50337502 5-(phenylethynyl)isoindolin-1-one::CHEMBL1682798

SMILES O=C1NCc2cc(ccc12)C#Cc1ccccc1

InChI Key InChIKey=CMSWIWJBEZTKAF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50337502   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337502(5-(phenylethynyl)isoindolin-1-one | CHEMBL1682798)
Affinity DataEC50:  51nMAssay Description:Positive allosteric modulation of mGlu5 receptor assessed as calcium mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Vanderbilt Medical Center

Curated by ChEMBL
LigandPNGBDBM50337502(5-(phenylethynyl)isoindolin-1-one | CHEMBL1682798)
Affinity DataEC50:  30nMAssay Description:Positive allosteric modulation of human mGlu4 receptor expressed in human HEK293 cells assessed as potentiation of glutamate-induced calcium mobiliza...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed