BDBM50351547 CHEMBL1223751
SMILES CCOc1ccc(OCC(O)CN(C)Cc2c(C)nn(Cc3ccccc3Cl)c2C)cc1
InChI Key InChIKey=UOKIJOWYTBNPIM-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50351547
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as probeMore data for this Ligand-Target Pair
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of LPS-induced TLR4 activation in mouse RAW264.7 cells assessed as reduction in NO production after 18 to 24 hrsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using bufuralol as probeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as probeMore data for this Ligand-Target Pair
Affinity DataIC50: 3.42E+4nMAssay Description:Antagonist activity at human TLR4 expressed in HEK blue cells coexpressing MD-2/CD14 assessed as inhibition of LPS-induced NF-kappaB activation-media...More data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-8 release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of TNFalpha release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+5nMAssay Description:Inhibition of LPS-induced TLR4 activation in human whole blood assessed as inhibition of IL-6 release preincubated for 5 to 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as probeMore data for this Ligand-Target Pair