BDBM50376747 CHEMBL409247

SMILES C[n+]1cc(NC(=O)c2cccc(n2)C(=O)Nc2c[n+](C)c3ccccc3c2)cc2ccccc12

InChI Key InChIKey=KPOOEJJPTYXNTN-UHFFFAOYSA-P

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50376747   

TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  63nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  52nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  45nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Institut National De La Sant£

Curated by ChEMBL
LigandPNGBDBM50376747(CHEMBL409247)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed