BDBM50377671 CHEMBL403221

SMILES CC(=O)Cn1nnnc1CNC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=CGBFZMKVQUAYOI-UHFFFAOYSA-N

Data  2 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50377671   

TargetCannabinoid receptor 2(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 channel expressed in human HEK293 cells assessed as elevation in intracellular calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at rat TRPA1 channel expressed in human HEK293 cells assessed as elevation in intracellular calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDiacylglycerol lipase-alpha(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG in COS cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50377671(CHEMBL403221)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of rat brain FAAH mediated [14C]anandamide hydrolysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed