BDBM50377956 CHEMBL1744356

SMILES Fc1ccc2cc(CN3[C@@H]4CC[C@@H]3CC(C4)NC(=O)c3ccccc3-c3cncnc3)ccc2c1

InChI Key InChIKey=KPKVUFKNQYKTLE-CLJLJLNGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50377956   

TargetC-C chemokine receptor type 3(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50377956(CHEMBL1744356)
Affinity DataIC50:  93nMAssay Description:Antagonist activity at CCR3 receptor expressed in mouse B300-19 cells assessed as inhibition of eotaxin-induced calcium influx by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50377956(CHEMBL1744356)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of human CYP2D6 by fluorescence technique in presence of NADPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed