BDBM50386200 CHEMBL2043240

SMILES NC(=O)CS(=O)Cc1ccccc1Oc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=JBKSEOCGJGAYMB-UHFFFAOYSA-N

Data  18 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50386200   

TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  2.16E+5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
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Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of rat DAT-mediated dopamine reuptakeMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetTransporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair

Target InfoReactome pathway
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Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetTransporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of rat NET-mediated norepinephrine reuptakeMore data for this Ligand-Target Pair

Target InfoReactome pathway
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Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
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TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of rat SERT-mediated serotonin reuptakeMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A5(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A5More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 3A5(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of CYP3A5More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  1.06E+5nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  2.16E+5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Cephalon (France)

Curated by ChEMBL

LigandBDBM50386200(CHEMBL2043240)Copy SMILESCopy InChI

Affinity DataIC50:  200nMAssay Description:Inhibition of rat DATMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sid

In DepthDetails ArticlePubMed
Copy BDB DOI