BDBM50387116 4-ureidophenyl sulfamate ring derivative 3x::CHEMBL2047798

SMILES NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1

InChI Key InChIKey=MFOAVNTXCHPXMK-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50387116   

TargetCarbonic anhydrase 12(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  5nMAssay Description:Inhibition of human carbonic anhydrase-12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  5nMAssay Description:Inhibition of human carbonic anhydrase 12 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  5nMAssay Description:Inhibition of human recombinant transmembrane CA12 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  11nMAssay Description:Inhibition of human carbonic anhydrase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  12nMAssay Description:Inhibition of human carbonic anhydrase 9 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  12nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
Birla Institute of Technology

LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant transmembrane CA9 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  271nMAssay Description:Inhibition of human carbonic anhydrase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  291nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  291nMAssay Description:Inhibition of human recombinant cytosolic CA2 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universit£

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  505nMAssay Description:Inhibition of recombinant full length Candida albicans NCE103 expressed in Escherichia coli BL21 preincubated for 15 mins by stopped-flow CO2 hydrase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of human carbonic anhydrase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  2.87E+3nMAssay Description:Inhibition of human recombinant cytosolic CA1 preincubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Romanian Academy

Curated by ChEMBL
LigandPNGBDBM50387116(4-ureidophenyl sulfamate ring derivative 3x | CHEM...)
Affinity DataKi:  2.87E+3nMAssay Description:Inhibition of human carbonic anhydrase 1 preincubated for 15 mins measured for 10 to 100 sec using phenol red indicator-based stopped flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed