BDBM50393258 CHEMBL2151734

SMILES C[C@@H](N(C)C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N(C)CC(N)=O

InChI Key InChIKey=UNKNXDWBSNQELQ-LEOXJPRUSA-N

Data  3 KI  2 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50393258   

TargetMu-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]diprenorphine from human MOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]diprenorphine from human DOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataKi: >1.00E+6nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cell membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  0nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  0.287nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataIC50:  4.90nMAssay Description:Displacement of [3H]deltorphin2 from DOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]naloxone from MOR in rat brain homogenates by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  0.0790nMAssay Description:Agonist activity at human MOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  4.40E+3nMAssay Description:Agonist activity at human DOR expressed in HEK293 cell membrane assessed as inhibition of forskolin-induced cAMP accumulation by by liquid scintillat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed