BDBM50394305 CHEMBL2159382

SMILES COc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(cc2)C(N)=N)cc1OC

InChI Key InChIKey=AYQFZKJULLPHPY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394305   

TargetProthrombin(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50394305(CHEMBL2159382)
Affinity DataKi:  1.87E+5nMAssay Description:Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransmembrane protease serine 6(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50394305(CHEMBL2159382)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed