BDBM50412102 CHEMBL495255

SMILES CCCNc1ccc(cc1-c1nc2cc(ccc2o1)-c1ccc(F)cc1)N1C(=O)c2ccc(cc2C1=O)C(O)=O

InChI Key InChIKey=KGVSTFTVOJYOKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50412102   

TargetHeparanase(Homo sapiens (Human))
Centro De Investigaci�N Pr�Ncipe Felipe

Curated by ChEMBL
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeparanase(Homo sapiens (Human))
Centro De Investigaci�N Pr�Ncipe Felipe

Curated by ChEMBL
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50:  200nMAssay Description:Inhibition of human heparanase assessed as reduction in basic fibroblast growth factor binding incubated for 2 hrs by microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHeparanase(Homo sapiens (Human))
Centro De Investigaci�N Pr�Ncipe Felipe

Curated by ChEMBL
LigandPNGBDBM50412102(CHEMBL495255)
Affinity DataIC50:  501nMAssay Description:Inhibition of heparanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed