BDBM50421196 CHEMBL2087285

SMILES OC(=O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccccc3)cc2)Cc2cc(F)cc(F)c2)c(Br)c1

InChI Key InChIKey=LHQBVGUGVONUIH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50421196   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421196(CHEMBL2087285)
Affinity DataIC50:  722nMAssay Description:Displacement of [3H]dexamethasone from human glucocorticoid receptor expressed in baculovirus infected Sf9 cells after overnight incubation by scinti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(RAT)
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421196(CHEMBL2087285)
Affinity DataIC50:  3.90E+3nMAssay Description:Antagonist activity at glucocorticoid receptor in rat hepatocytes assessed as inhibition of dexamethasone-induced trypsine aminotransferase expressio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Zydus Research Centre

Curated by ChEMBL
LigandPNGBDBM50421196(CHEMBL2087285)
Affinity DataIC50:  1.05E+3nMAssay Description:Antagonist activity at human glucocorticoid receptor expressed in GRAF cells assessed as inhibition of dexamethasone-induced alkaline phosphatase exp...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed