BDBM50427303 CHEMBL2325722
SMILES CS(=O)(=O)C1(CC1)c1cc(nc(n1)-c1cccc2[nH]c(cc12)C(N)=O)N1CCOCC1
InChI Key InChIKey=YPPJXPIUZCFOSQ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50427303
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of ATR-mediated CHK1 phosphorylation at serine 345 in human HT29 cells after 1 hr in presence of 4-nitroquinoline 1-oxideMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ATR in human HeLa cell nuclear extracts using glutathione S-transferase-p53N66 and ATP as substrate incubated for 10 mins prior to ATP ...More data for this Ligand-Target Pair