BDBM50430131 CHEMBL2338255

SMILES CC1(C)CCN([C@H]2C3CC4CC2C[C@@](O)(C4)C3)C(=O)c2cnn(c12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=SRZJPLQHGQKYHU-JWCGBNDWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50430131   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430131(CHEMBL2338255)
Affinity DataIC50:  20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50430131(CHEMBL2338255)
Affinity DataIC50:  29nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells using cortisone and NADPH as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed