BDBM50433412 CHEMBL2380649

SMILES NC(=O)[C@@]12CC3CC(C1)[C@H](NC(=O)N1CCN(c4ccc(cn4)N4CCN(CC4)S(=O)(=O)C4CC4)c4ccccc14)C(C3)C2

InChI Key InChIKey=AKWMGLFHWVBCBK-YUIFXIQYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50433412   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Rattus norvegicus (rat))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  9nMAssay Description:Inhibition of rat 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Sanofi R & D

Curated by ChEMBL
LigandPNGBDBM50433412(CHEMBL2380649)
Affinity DataIC50:  8nMAssay Description:Inhibition of mouse recombinant 11beta-HSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed