BDBM50457314 CHEMBL4211990
SMILES CN1CC(F)C(C1)Oc1ccc(cc1Nc1nccc(n1)-c1cc2c(NC[C@]2(C)CO)c(c1)C#N)C#N
InChI Key InChIKey=WLCMCSHKIUOQHF-LGYSXGNESA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50457314
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant human GST-tagged MAP3K14 autophosphorylation after 1 hr by Alpha screen assayMore data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of MAP3K14 in human L363 assessed as decrease in IKKalpha phosphorylation level after 2 hrs by sandwich immuno assayMore data for this Ligand-Target Pair