BDBM50459580 CHEMBL4211893

SMILES CC(C1CC1)n1cc(Nc2nc(N)nc(n2)-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)cn1

InChI Key InChIKey=WSOQWKRFBWBAMY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50459580   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50459580(CHEMBL4211893)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells at holding potential of -80 mV by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50459580(CHEMBL4211893)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated activated human recombinant BTK using FITC-labeled Srctide peptide substrate by mobility shift ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

Curated by ChEMBL
LigandPNGBDBM50459580(CHEMBL4211893)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of N-terminal DYKDDDDK tagged biotinylated unactivated human recombinant BTK using FITC-labeled Srctide peptide substrate by by mobility s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed